We review the diagnostic utility of various MRI techniques in patients with cryptogenic stroke.

We report a fascinating case of APLS vasculopathy with vessel wall MR imaging findings.

We describe how to use principles of implementation science and the RE-AIM framework to succssfully build a clinical vessel wall imaging program at an academic medical center.

We report scalp and orbital MR findings in a patient with giant cell arteritis with inflammation of the temporal and ophthalmic arteries.

In this post hoc analysis of the Factor VIIa for Acute Hemorrhagic Stroke Treatment (FAST) trial, early PHE expansion and trajectory in men were significantly higher than women.

We review the embryology of the intracranial arteries, spectrum and vessel wall imaging appearances of intracranial arterial diseases and highlight future research directions on understanding the temporal profile of VWI findings and developing quantitative interpretative approaches.

In this multicenter study evaluating patients with GCA and imaged with VWI, up to 14.5% of patients showed intracranial inflammatory vessel wall changes.

We review imaging features by imaging modality (TEE, CT/CTA, MR/MRA) of complex aortic plaque. The prevalence of complex aortic plaque is also calculated in patients with embolic stroke of undetermined source. See twitter teaser here.

In this international collaborative work, we report a new Plaque-RADS nomenclature to classify carotid plaque types based on composition and morphology via different imaging modalities, such as US, CT, and MRI.

We report the speed and accuracy of a novel web-based software for streamlined single-click calcific plaque labeling compared to manual segmentation using 3D slicer. (Open Source)

We review the clinical applications for intracranial VWI and interpretive pearls and technical pitfalls for this innovative imaging technique.

We systematically review all orbital MRI findings of patients with biopsy-proven GCA and visual disturbances. We report the clinical/exam findings and prevalence of orbital imaging findings in this disease.

We review diagnostic tests used for giant cell arteritis, including imaging, lab, and histopathology.

This multicenter study examines orbital MRI findings using black blood (vessel wall) MRI in patients with Giant Cell Arteritis. Figure shows enhancement of the ophthalmic artery using VW-MRI (arrows).

We report how VWI can facilitate diagnosis of a craniocervical vertebral artery dissection.

We review intracranial, carotid, and aortic vessel wall MR imaging techniques used to identify culprit plaque in patients with ESUS. View animated visual abstract here.

We report imaging findings on CTA and VWI of a carotid web that was the most likely cause of ischemic stroke.

This multicenter (China and USA) retrospective study evaluates sex-differences in intracranial plaque burden in hypertensive patients with acute ischemic stroke.

We review vessel wall MR imaging (VWI) features of different intracranial vasculopathies and show illustrative clinical cases.

In collaboration with Dr. Javier Romero’s team at MGH/HMS, this work used high-resolution vessel wall imaging to determine associations between cardiovascular risk factors and specific intracranial vessel segment involvement.

Accuracy is an important parameter of a diagnostic test. We provide a framework for evaluating potential sources of study design biases that are found in diagnostic accuracy studies and explain their impact on sensitivity and specificity estimates.

We systematically review the vessel wall MR imaging literature to assess the criteria and measurement methods of VWI-related imaging endpoints for symptomatic intracranial plaque in patients with ischemic events.

We examined sex differences in nonstenotic carotid plaque composition in patients with embolic stroke of undetermined source.

We systematically reviewed the literature on vessel wall MR imaging patterns of inflammatory versus infectious vasculitis and also compared imaging patterns for intracranial versus extracranial arteries of the head and neck.

We report a case that highlights the role vessel wall MR imaging can play in detecting small ruptured aneurysms that intermittently thrombose and are otherwise challenging to diagnose with conventional vessel imaging.

We report a case that highlights the utility of vessel wall MR imaging in detecting nonstenotic basilar artery plaque contributing to an acute pontine infarct.

We performed a meta-analysis to evaluate the strength of association of imaging features of symptomatic plaque leading to downstream ischemia.

We report a case highlighting the role of high-resolution vessel wall MR imaging as a useful adjunct to conventional lumen-based imaging techniques for diagnosing arterial dissections.

We review Ya et al’s work entitled, “High-resolution combined arterial spin-labeling MR for identifying cerebral arterial stenosis induced by moyamoya disease or atherosclerosis.”

For neuroimaging applications, loss adaptive dipole inversion (LADI) preserved image sharpness and fine features in patients with glioblastoma and microbleeds. LADI performed better at mitigating artifacts in cardiac QSM. This work was in collaboration with and led by members of Dr. Walter Witschey’s CorLab.

In this review, we discuss the advantages of intracranial vessel wall MR imaging for intracranial atherosclerosis, the potential of bioimaging markers to identify vulnerable intracranial plaque, and future directions of artificial intelligence and its utility for lesion scoring and assessment.

We systematically review the literature to identify trends and extent of variability in intracranial vessel wall MR imaging techniques and protocols.

We performed a systematic review of publication trends and reporting quality of VWI publications to identify unmet needs and future directions.

Sspatial distribution of vessel wall enhancement is an important consideration when interpreting vessel wall MR exams, particularly in patients with a comorbid diagnosis of hypertension.

This case illustrates the radiologic evolution of tuberculous vasculitis by serial vessel wall imaging,

We review the salient clinical and imaging features of noninflammatory and inflammatory CNS vasculopathies.

3D-TOF-MRA and vessel wall MR imaging together identifies a higher number of abnormal vessel segments than 3D-TOF-MRA alone and may provide a more accurate assessment of disease burden.

We present a case of intracranial hemorrhage presumably due to intracranial atherosclerotic disease identified by vessel wall MR imaging and silent on lumen-based imaging modalities.

We show a case of a patient with VZV vasculitis imaged with high resolution vessel wall magnetic resonance imaging. There was circumferential wall thickening and enhancement of the infected vessels.